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History. Shipping portals first emerged in 2000-2001 when CargoSmart, GT Nexus and INTTRA Inc. all launched their trial phases. [citation needed]Portal members. Membership across the three main shipping portals comprises 30 carriers of varying sizes, but the majority are amongst the world's largest, so most of the industry's TEU capacity is represented.
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Louisville has emerged as a major center for the health care and medical sciences industries. Louisville has been central to advancements in heart and hand surgery as well as cancer treatment. Some of the first artificial heart and hand transplants were conducted in Louisville. The James Graham Brown Cancer Center is well-renowned.