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Arizona (/ ˌ ær ɪ ˈ z oʊ n ə / ⓘ ARR-iz-OH-nə; Navajo: Hoozdo Hahoodzo [hoː˥z̥to˩ ha˩hoː˩tso˩]; [10] O'odham: Alĭ ṣonak [ˈaɭi̥ ˈʂɔnak]) [11] is a state in the Southwestern region of the United States, sharing the Four Corners region of the western United States with Colorado, New Mexico, and Utah.
Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4][8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
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The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that each last from days to weeks. [4][5] If the elevated mood is severe or associated with psychosis, it is called mania; if it is less severe and does not significantly affect functioning ...
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