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  2. Fentanyl - Wikipedia

    en.wikipedia.org/wiki/Fentanyl

    The patches work by slowly releasing fentanyl through the skin into the bloodstream over 48 to 72 hours, allowing for long-lasting pain management. [42] Dosage is based on the size of the patch, since, in general, the transdermal absorption rate is constant at a constant skin temperature. [42] Each patch should be changed every 72 hours. [43]

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